Cerebellar liponeurocytoma with high proliferation index: treatment options.

First described by Bechtel and collaborators1, cerebellar liponeurocytomas are posterior fossa lesions composed of densely packed neuronal cells admixed with foci of welldifferentiated adipocyte-like cells. Similar tumors have also been referred to as lipomatous medulloblastoma, lipidized medulloblastoma, medullocytoma, neurolipocytoma, lipomatous glioneurocytoma, or lipidized mature neuroectodermal tumor of the cerebellum2-8. These different appellations reflect the histopathological similarities between liponeurocytomas, medulloblastomas and central neurocytomas. However, cerebellar liponeurocytoma is genetically distinct from medulloblastoma and central neurocytoma9; it is now recognized as a separate entity by the World Health Organization10. Because of the small number of reported cases, the proper management of cerebellar liponeurocytoma, especially when subtotally resected, remains to be elucidated. We report the case of a patient with a hemispheric cerebellar liponeurocytoma in which the proliferation index contributed to the decision to use adjuvant radiotherapy after gross total resection.